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     FOREVER Lodhra

Sympiocos racemosa
Sanskrit  : Lodhra
English  : Symplocus bark
Latin name : Sympiocos racemosa
Family : Symplocaceae
Ayurvedic Pharmacodynamic properties
Rasa : Kashaya (astringent) 
Guna : Laghu (light), Ruksha (dry)
Virya : Shita (cold)
Vipaka : Katu (pungent)
Doshakarma : Kapha-pittashamak (alleviate K and P Dosha)
Useful parts : Bark

Medicinal uses     

 

 

 

 

 

:

 

 

 

 

 

 It is astringent, cold, eye protective, anti-inflammatory and Grahi in properties. The plant and its formulations are used in diarrhoea, dysentery, bleeding piles, menorrhagea, metrorrhagea, leucorrhoea, blood disorders, skin disorders, bleeding per any opening of the body like epistaxis, for wound healing and to stop haemorrhage. It is also used in skin and eye infections.
Dose

:

Churna (powder) 1-3 gm.
Important formulations

:

Lodhrasava, Lodhradi Kwatha

Uses as home remedy:

  1. In meno and metrorrhagea, its bark powder 1 gm should be taken along with Mishri (a type of sugar).
  2. In oedema and inflammation, its paste should be applied at the same.
  3. In gingivitis and bleeding through gums, its decoction should be kept in mouth (Gandush) and its paste along with Rasanjana and Nagarmotha also should be pasted at the same.

Recent studies

1: Nat Prod Res. 2005 Jul;19 (5):509-15. Lipoxygenase inhibiting ethyl substituted glycoside from Symplocos racemosa. Abbasi MA, Ahmad VU, Zubair M, Nawaz SA, Lodhi MA, Farooq U, Choudhary MI. HEJ Research Institute of Chemistry, International Center for Chemical Sciences University of Karachi, Karachi 75270, Pakistan. atrabbasi@yahoo.com

Phytochemical investigation of Symplocos racemosa resulted in the isolation of a new ethyl substituted glycoside, 1-ethyl brachiose-3'-acetate (1) along with four known compounds ketochaulmoogric acid (2), nonaeicosanol (3), triacontyl palmitate (4) and methyl triacontanoate (5). The substitution of ethyl group on 1 was natural because during the course of extraction and purification ethanol was not used. The structural elucidation of the isolated compounds was based primarily on 1D- and 2D-NMR analysis, including COSY, HMQC, and HMBC correlations. The glycoside 1 and triacontyl palmitate (4) displayed the inhibitory potential against lipoxygenase and urease enzyme, respectively. PMID: 15938197 [PubMed - indexed for MEDLINE]

2: Int J Low Extrem Wounds. 2003 Mar;2(1):25-39. Plant medicines of Indian origin for wound healing activity: a review. Biswas TK, Mukherjee B. Department of Sharira Kriya, J. B. Roy State Ayurvedic Medical College and Hospital.

Research on wound healing drugs is a developing area in modern biomedical sciences. Scientists who are trying to develop newer drugs from natural resources are looking toward the Ayurveda, the Indian traditional system of medicine. Several drugs of plant, mineral, and animal origin are described in the Ayurveda for their wound healing properties under the term Vranaropaka. Most of these drugs are derived from plant origin. Some of these plants have been screened scientifically for the evaluation of their wound healing activity in different pharmacological models and patients, but the potential of most remains unexplored. In a few cases, active chemical constituents were identified. Some Ayurvedic medicinal plants, namely, Ficus bengalensis, Cynodon dactylon, Symplocos racemosa, Rubia cordifolia, Pterocarpus santalinus, Ficus racemosa, Glycyrrhiza glabra, Berberis aristata, Curcuma longa, Centella asiatica, Euphorbia nerifolia, and Aloe vera, were found to be effective in experimental models. This paper presents a limited review of plants used in Ayurvedic medicine. PMID: 15866825 [PubMed]

3: J Ethnopharmacol. 2004 Sep;94(1):197-200. Effect of Symplocos racemosa Roxb. on gonadotropin release in immature female rats and ovarian histology. Bhutani KK, Jadhav AN, Kalia V. Department of Natural Product, NIPER, Sect. 67, Phase X, SAS Nagar (Mohali) Near Chandigarh, Punjab 160062, India. kkbhutani@usa.net

In the present study we are reporting in vivo effect of aqueous extracts of Symplocos racemosa Roxb. (Fam. Symplocaceae) on serum FSH and LH levels in immature female Sprague-Dawley rats under basal conditions. Symplocos racemosa is used in Indian System of Medicine (ISM) for various female disorders. Aqueous extract on oral administration significantly stimulated serum FSH level (P < 0.016) along with the rise in serum LH level (P < 0.001). Moreover, histopathological studies revealed enhanced folliculogenesis, presence of mature follicles and detached oocytes, which are result of increased FSH and LH levels. Further, an increase in the ovary weight of treated animals was found due to observed FSH surge. These results are in concordance with the traditional use of the drug for female disorders. PMID: 15261983 [PubMed - indexed for MEDLINE]

4: Phytochemistry. 2003 May;63(2):217-20. Phenolic glycosides from Symplocos racemosa: natural inhibitors of phosphodiesterase I. Ahmad VU, Abbasi MA, Hussain H, Akhtar MN, Farooq U, Fatima N, Choudhary MI. H.E.J. Research Institute of Chemistry, International Center for Chemical Sciences, University of Karachi, Karachi-75270, Pakistan. vuahmad@cyber.net.pk

One new phenolic glycoside named benzoylsalireposide (1) along with one known phenolic glycoside named salireposide (2) have been isolated from Symplocos racemosa. Four other known compounds i.e. beta-amyrin (3), oleonolic acid (4), beta-sitosterol (5) and beta-sitosterol glycoside (6) were also isolated from this plant. The structure elucidation of the isolated compounds was based primarily on 1D- and 2D-NMR analysis, including COSY, HMQC, and HMBC correlations. The compound 1 and 2 showed inhibitory activity against snake venom phosphodiesterase I. PMID: 12711144 [PubMed - indexed for MEDLINE]

5: Indian J Physiol Pharmacol. 1964 Jul;8(3):181-8. Preliminary phytochemical and pharmacological study of Symplocos racemosa (Roxb.). Mishra SS, Bapat SK, Tewari JP. PMID: 5831718 [PubMed - indexed for MEDLINE]
Summary:
Symplocos racemosa is used in Indian System of Medicine (ISM) for various female disorders. Recent studies show that the Lodhra has powerful antidiarrhoeal properties. It is safely effective in wound healing. It is also proved to cure bleeding piles, leucorrhoea, metrorrhagea and menorrhagea. The standard doses are well tolerated.


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